Viruses and Targets
The Projects in MAVDA will focus on unique and complementary approaches to develop, characterize, and optimize small molecules for the treatment of SARS-CoV-2, other CoVs, as well as additional RNA virus families of pandemic potential. The viruses and targets covered under the program are listed below.
Virus Family: Coronaviridae
![](/-/media/project/hmh/hmh/mavda/mavda/virusesandtargets-coronaviridae-sars-cov-2/cta-virusesandtargets-coronaviridae_800x800.jpg)
SARS-CoV-2
HCoV-NL63
HCoV-229E
HCoV-0C43
MERS
Virus Family: Flaviviridae
![](/-/media/project/hmh/hmh/mavda/mavda/virusesandtargets-flaviviridae-westnile/cta-virusesandtargets-flaviviridae-westnile_800x800.jpg)
DENV1-4
ZIKV
WNV
YFV
POWV
LGTV
Virus Family: Poxviridae
![](/-/media/project/hmh/hmh/mavda/mavda/monkeypox_650x250/monkeypox_800x800.jpg)
MPV
Virus Family: Togaviridae
![](/-/media/project/hmh/hmh/mavda/mavda/mavda-virustsandtargets-togoviridaechikungunya.jpg)
CHIKV
EEEV
SINV
VEEV
SFV
RRV
MAYV
ONNV
Targets:
3CL pro (Mpro)
NSP14 Methylase
PL pro; Helicase
RdRp
Exonuclease